HCP Aging / Aging Adult Brain Connectome (AABC)

AABC Release 2 includes cross-sectional (V1) and longitudinal (V2, V3, V4) 3T MR scans and non-imaging phenotypic data from 1396 typically aging adults (ages 36-90+) in the HCP-Aging (HCA) and Aging Adult Brain Connectome (AABC) projects adding 632 sessions bringing the total to 2878 -- 1396 V1, 915 V2, 471 V3, and 96 V4 sessions. 

It includes imaging for all included modalities from 1390 participants in 2789 sessions (42+ TB of data total) and non-imaging data collected over a broad range of domains at imaging and non-imaging events. See subject breakdowns for visit counts and event sequence.

 What’s new in AABC Release 2?

• Preprocessed and unprocessed structural MRI, resting state fMRI, task fMRI, diffusion MRI, ASL, and high-res hippocampal T2 [unprocessed only] data in modality-specific "HCP package" datasets downloadable from BALSA.

  • Most users should access Preprocessed Recommended fMRI data that have been cleaned of spatially and temporally specific structured noise and precisely aligned across subjects by multimodal cortical surface registration (MSMAll) using HCP pipelines that have been developed specifically for HCP-style data.

• 3T Multi-modal Imaging Derived Phenotypes (IDPs) for released participant sessions available in CSV (zip archives in IDPs tab) and Connectome Workbench-compatible CIFTI imaging package formats.
• 7 T Magnetic Resonance Spectroscopy (MRS) brain metabolite data are available for 282 participant visits.
• Non-imaging behavioral and biomeasure data available for released participant sessions and follow up events. 

  • Core Variables, high interest primary variables and summary scores, can be viewed and filtered in the BALSA UI

    • includes MRS brain metabolites and per subject completeness of all datatypes

    • use Column Selector to add, Export CSV to download all Core Variables or selected subset).

  • >3,000 Extended (XL) variables and accompanying Data Dictionary, including item-level and follow up event variables, for all participant events available in comprehensive spreadsheets.

  • NIH Toolbox raw and score data for in-person visits are available as spreadsheets/zip archive.
• Visualization instructions and HCA1798 group average template data for visualizing HCP pipelines output, including IDPs, in Connectome Workbench wb_view.

Get Access and Download the data: Get started by Registering for BALSA, click on the “ConnectomeDB” tab, and agree to the AABC Data Use Terms. An academic, non-profit, or government email address is required to agree to the AABC Data Use Terms and access the data.

To download imaging data, you must 1) install Aspera Connect (scroll down to “IBM Aspera client-deployed software” to find Aspera Connect download links) and 2) an Aspera Connect plugin for your browser (available from Firefox, Chrome, Safari, etc.). 

Set Preferences>Transfers in Aspera Connect to a directory with sufficient space for large downloads. 

Use the Column Selector and Export CSV to view, filter on, and download all or subsets of Core Variables for selected subjects. 

To download the full non-imaging data, click the Files tab and Download under AABC_Release2_Non-imaging_Data-XL.csv.

Want more information?  Check out our updated documentation to help with understanding the file structure and interpreting the data.

Join the Community. If you are actively using HCP data and tools, we encourage you to join and be active in the HCP-Users Google group, so that you can tune in to technical discussions on issues that may be of interest. Once you have joined (posts from nonmembers are moderated to control spam), post questions to hcp-users@humanconnectome.org.   

Share your Analyses. As you work with AABC data and prepare your work for publication, we encourage you to use Connectome Workbench to prepare your figures as scenes and upload your scenes as a BALSA dataset that can be linked from your publication. Don’t forget to cite the HCA and AABC grants and BALSA in your manuscript!

AABC Release 1 includes cross-sectional (V1) and longitudinal (V2, V3) 3T MR scans and non-imaging data from 1248 healthy older adults (ages 36-90+) in the HCP-Aging (HCA) and Aging Adult Brain Connectome (AABC) projects.

It includes multi-modal preprocessed and unprocessed imaging data (structural, high-res hippocampal T2 [unprocessed only], resting state fMRI, task fMRI, diffusion, and ASL) on 1248 participants in 2214 imaging visits (many subjects have data for more than one visit, 36+ TB of data). It includes non-imaging data collected over a broad range of domains for 1248 V1, 762 V2, and 236 V3 (2246 total) in-person visits and in remote follow up surveys (non-imaging events). Session breakdowns by study and visit/event are available here.

What’s new in AABC Release 1?

• New ConnectomeDB powered by BALSA data sharing platform (see ConnectomeDB tab) that displays and allows filtering of non-imaging Core Variables for creating subject groups
• Preprocessed and unprocessed multimodal MRI data [structural MRI, resting state fMRI, task fMRI, diffusion MRI, and arterial spin labeling (ASL) MRI] 
  • Most users should access Preprocessed Recommended data that have been cleaned of spatially and temporally specific structured noise and precisely aligned across subjects by multimodal cortical surface registration (MSMAll)
• 3T Multi-modal Imaging Derived Phenotypes (IDPs) for released participant sessions available in CSV (zip archives in IDPs tab) and Connectome Workbench-compatible CIFTI imaging package formats
• Harmonized non-imaging behavioral and biomeasure data available for participant visits and follow up events across HCA and AABC to facilitate cross-sectional and longitudinal analyses across all participants
  • Core Variables, high interest primary variables and summary scores, can be viewed and filtered in the BALSA UI (use Column Selector to add, Export CSV to download)
    • Completeness variables indicate the per subject availability of data types to be used to create subject groups
    • 7 T Magnetic Resonance Spectroscopy (MRS) brain metabolite data are available for 138 participants
      
  • Extra long (XL) set of non-imaging data (including item-level and follow up events/variables) along with NIH-Toolbox raw and score outputs are available as spreadsheets

Get Access and Download the data: Get started by Registering for BALSA and agreeing to the AABC Data Use Terms. An academic, non-profit, or government email address is required for agreement to the AABC Data Use Terms and accessing the data.

To download imaging data, you must 1) install Aspera Connect (scroll down to “IBM Aspera client-deployed software” to find Aspera Connect download links) and 2) an Aspera Connect plugin for your browser (available from Firefox, Chrome, Safari, etc.). 

Set Preferences>Transfers in Aspera Connect to a directory with sufficient space for large downloads.

To download the full non-imaging data, click the Files tab and Download under AABC_Release1_Non-imaging_Data-XL.csv. Use the Column Selector and Export CSV to view, filter on, and download all or subsets of Core Variables for selected subjects.

Want more information?  Check out our updated documentation to help with understanding the file structure and interpreting the data.

Lifespan HCP Release 2.0 includes cross-sectional visit 1 (V1) preprocessed structural and functional imaging data, unprocessed V1 imaging data for all included modalities (structural, high-res hippocampal T2, resting state fMRI, task fMRI, diffusion, and ASL), and non-imaging demographic and behavioral assessment data from 725 HCP-Aging (HCP-A, ages 36-100+) healthy participants (22+ TB of data). 

What’s new in the Lifespan 2.0 release?

• Preprocessed rfMRI and tfMRI data available for ALL release subjects
• Processed sMRI and fMRI data in modality- and processing output-specific "HCP package" datasets 
  • HCP packages cater to different analysis purposes can be used as filters on the Lifespan 2.0 NDA Query page to create custom download packages 
       
  • Most users should access Preprocessed Recommended data that have been cleaned of spatially specific structured noise and precisely aligned across subjects by multimodal cortical surface registration (MSMAll)  
      
• Behavioral and biomeasure data available for all released subjects, including NIH Toolbox measures for most subjects. 

Get Access and Download the data: Get started with the Data Access and Download Instructions for navigating NDA and using it's download tools. We've also created a wiki that details setup for downloading data via NDA's command line tools.

Want more information?  Check out our updated documentation to help with understanding the file structure and interpreting the data.